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Principal Investigator, Clinical Research Salary

Six-figure salaries are the norm for Clinical Research Principal Investigators in the United States, with median pay hovering around $102K per year. For the most part, Clinical Research Principal Investigators enjoy their work and report high levels of job satisfaction. Most report receiving medical coverage from their employers and a strong majority collect dental insurance. Women make up a slight majority of Clinical Research Principal Investigators (52 percent) survey respondents. The data for this synopsis comes from respondents who took the PayScale salary survey.

$74,362 - $191,550
MEDIAN: $101,944

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National Salary Data (?
XAll compensation data shown are gross, national 10th to 90th percentile ranges. Pay can vary greatly by location. To view local data, take the PayScale survey.
$74,362 - $191,550  
$0.00 - $20,273  
Total Pay (?
XTotal Pay combines base annual salary or hourly wage, bonuses, profit sharing, tips, commissions, overtime pay and other forms of cash earnings, as applicable for this job. It does not include equity (stock) compensation, cash value of retirement benefits, or the value of other non-cash benefits (e.g. healthcare).
$73,688 - $192,562  
Country: United States | Currency: USD | Updated: 2 May 2015 | Individuals Reporting: 46

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Pay by Experience Level for Principal Investigator, Clinical Research

Median of all compensation (including tips, bonus, and overtime) by years of experience.

For Clinical Research Principal Investigators, more experience in the field does not usually mean bigger paychecks. Salaries of relatively inexperienced workers fall in the neighborhood of $95K, but folks who have racked up five to 10 years see a notably higher median of $116K. After working for 10 to 20 years, Clinical Research Principal Investigators make a median salary of $130K. Clinical Research Principal Investigators with more than 20 years of experience report incomes that are only modestly higher; the median for these old hands hovers around $135K.

United States (change)

Experience Affects Principal Investigator, Clinical Research Salaries

up arrow 22%

up arrow 17%

up arrow 5%

National Average

up arrow 14%

Job Satisfaction

Extremely satisfied
Rated 5 out of 5
based on 5 votes.


52 %
48 %

Years of Experience

Less than 1 year
1-4 years
5-9 years
10-19 years
20 years or more

Common Health Benefits

medical benefits Medical: 86% dental benefits Dental: 71%
vision benefits Vision: 57% employee benefits None: 14%